Operator Health Index

Platelet-Rich Plasma (PRP)

The Rundown:

PRP therapy harnesses the body’s own healing properties by concentrating platelets and growth factors from the patient’s blood, offering a minimally invasive approach to pain management and tissue regeneration.

Why it Matters:

PRP therapy matters in pain management because it provides a natural, minimally invasive approach to alleviating chronic pain by promoting tissue repair and regeneration, offering patients an alternative to traditional treatments with potentially fewer side effects and long-term benefits.

Medical Synopsis:

Platelet-rich plasma (PRP) therapy has emerged as a cutting-edge treatment in the fields of pain management and regenerative medicine. This innovative procedure utilizes the body’s own healing properties to alleviate pain and stimulate tissue repair, offering new hope for patients suffering from a variety of musculoskeletal conditions.

Understanding Platelet-Rich Plasma (PRP):

PRP is a concentrated solution derived from the patient’s own blood, enriched with a high concentration of platelets, growth factors, and other bioactive proteins essential for tissue repair and regeneration. Platelets play a crucial role in the body’s natural healing process, releasing growth factors that promote cell proliferation, angiogenesis (formation of new blood vessels), and tissue remodeling.

Chronic pain conditions, such as osteoarthritis, tendon injuries, ligament sprains, and musculoskeletal disorders, can significantly impair a person’s quality of life. Traditional pain management approaches often involve medication, physical therapy, or surgical interventions, which may not always provide satisfactory results or carry risks of adverse effects. PRP therapy offers a non-invasive and holistic alternative by harnessing the body’s innate healing abilities to address the underlying cause of pain.

Harvesting and Injection Process:

The PRP harvesting process begins with a simple blood draw from the patient’s arm, similar to a routine blood test. The collected blood is then centrifuged to separate the platelets and plasma from other blood components, resulting in a concentrated PRP solution.

Once prepared, the PRP is carefully injected into the targeted area of injury or pain under ultrasound or fluoroscopic guidance to ensure precise placement and optimal outcomes. The injection site may vary depending on the specific condition being treated, such as the knee joint for osteoarthritis or the Achilles tendon for tendinopathy.

Clinical Studies and Outcomes:

Numerous clinical studies have demonstrated the efficacy of PRP therapy in treating various musculoskeletal conditions and promoting tissue regeneration. A randomized controlled trial published in the American Journal of Sports Medicine found that PRP injections significantly improved pain and function in patients with chronic lateral epicondylitis (tennis elbow) compared to corticosteroid injections.

Similarly, a meta-analysis published in the Journal of Orthopaedic Surgery and Research concluded that PRP therapy was effective in reducing pain and improving functional outcomes in patients with knee osteoarthritis. Furthermore, PRP injections have shown promising results in accelerating the healing of acute musculoskeletal injuries, such as ligament sprains and muscle strains, leading to faster recovery and return to activity.

Platelet-rich plasma (PRP) therapy represents a groundbreaking approach to pain management and tissue regeneration, offering patients a safe, minimally invasive, and effective alternative to conventional treatments. By harnessing the regenerative potential of the body’s own platelets and growth factors, PRP therapy holds promise as a transformative intervention in the field of musculoskeletal medicine, improving outcomes and restoring function for individuals suffering from a wide range of conditions.

Written by: Joey Fio, Chief Programs Officer

References

[1] Mishra AK, Skrepnik NV, Edwards SG, et al. Efficacy of Platelet-Rich Plasma for Chronic Tennis Elbow: A Double-Blind, Prospective, Multicenter, Randomized Controlled Trial of 230 Patients. Am J Sports Med. 2014;42(2):463-471. doi:10.1177/0363546513494359

[2] Filardo G, Kon E, Pereira Ruiz MT, et al. Platelet-Rich Plasma Intra-articular Injections for Cartilage Degeneration and Osteoarthritis: Single- Versus Double-Spinning Approach. Knee Surg Sports Traumatol Arthrosc. 2012;20(10):2082-2091. doi:10.1007/s00167-011-1864-7

[3] Lana JFSD, Weglein A, Sampson SE, et al. Randomized Controlled Trial Comparing Hyaluronic Acid, Platelet-Rich Plasma and the Combination of Both in the Treatment of Mild and Moderate Osteoarthritis of the Knee. J Stem Cells Regen Med. 2016;12(2):69-78.

[4] Kon E, Mandelbaum B, Buda R, et al. Platelet-Rich Plasma Intra-articular Injection Versus Hyaluronic Acid Viscosupplementation as Treatments for Cartilage Pathology: From Early Degeneration to Osteoarthritis. Arthroscopy. 2011;27(11):1490-1501. doi:10.1016/j.arthro.2011.05.011

Commentary

PRP serves as a valuable adjunctive therapy when used in conjunction with other treatments. While many SEALs have undergone PRP therapy alone without notable effects on advanced trauma, its efficacy significantly improves when combined with localized injections of stem cells or exosomes, often leading to superior outcomes, particularly when self-reported.

More Resources

Recently added