Operator Health Index

Stellate Ganglion Block (SGB)

The Rundown:

Stellate ganglion block (SGB) is a minimally invasive procedure that has expanded from pain management to improving sleep quality by reducing sympathetic overactivity, showing promising outcomes in enhancing sleep duration and efficiency

Why it Matters:

SGB matters because it offers a novel, non-pharmacological approach to managing various conditions, including chronic pain, PTSD, anxiety, and sleep disturbances, by modulating the sympathetic nervous system, potentially providing relief where traditional treatments may have failed or caused undesirable side effects.

Medical Synopsis:

Stellate ganglion block (SGB) is a minimally invasive procedure that involves the injection of local anesthetics around the stellate ganglion, a collection of nerves in the neck that is part of the sympathetic nervous system. This technique has been traditionally used to treat pain and vascular conditions, but in recent years, its application has expanded to include the treatment of certain psychiatric conditions and sleep disturbances.

The historical context of SGB dates back to the early 20th century when it was first used for pain relief in conditions like complex regional pain syndrome (CRPS). Over the years, its utility has been recognized in treating a variety of conditions, including post-traumatic stress disorder (PTSD), hot flashes, and more recently, sleep disorders. The evolution of SGB from a pain management procedure to a broader therapeutic tool reflects its impact on the autonomic nervous system, which plays a significant role in regulating sleep patterns.

The mechanism by which SGB benefits sleep involves its effect on the sympathetic nervous system. By blocking the sympathetic fibers of the stellate ganglion, SGB can reduce sympathetic overactivity, which is often associated with stress, anxiety, and sleep disturbances. The reduction in sympathetic tone can lead to an increase in parasympathetic activity, promoting relaxation and enhancing the quality of sleep. Anecdotal evidence and some studies have reported improvements in sleep quality, including reduced time to fall asleep, increased sleep duration, and improved sleep efficiency.

Quantitatively, data supporting the benefits of SGB on sleep is still emerging, with most evidence being derived from studies on PTSD patients, where sleep disturbances are a common symptom. For instance, a study conducted on military personnel with PTSD showed that those who received SGB reported a significant improvement in sleep quality and a reduction in insomnia symptoms compared to those who did not receive the block. Participants reported a decrease in the time to fall asleep by an average of 30 minutes and an increase in total sleep time by approximately 1 hour. Moreover, subjective reports indicated a 50% improvement in sleep quality on scales such as the Pittsburgh Sleep Quality Index (PSQI).

Obtaining an SGB involves consulting with a healthcare provider who is experienced in performing the procedure, such as a pain management specialist, anesthesiologist, or psychiatrist with training in interventional techniques. The procedure is typically performed under ultrasound guidance to ensure accurate placement of the anesthetic, minimizing risks and enhancing the efficacy of the block.

Long-term usage of SGB, especially when used for conditions like sleep disturbances, is not well studied, and there are concerns about potential side effects and complications. The most common side effects include soreness at the injection site, temporary hoarseness, and Horner’s syndrome (ptosis, miosis, anhidrosis) on the side of the injection, which usually resolves within a few hours to days. Repeated blocks over time may pose a risk of diminishing returns, where the effectiveness of the block may decrease, or there may be a requirement for increased frequency of blocks to achieve the same therapeutic effect. There is also a theoretical risk of altering sympathetic nervous system function with repeated interventions.

In conclusion, SGB represents a promising but still emerging therapeutic option for individuals with sleep disturbances, particularly those related to sympathetic overactivity. While anecdotal and preliminary data suggest potential benefits, more rigorous and controlled studies are needed to quantify its efficacy, optimal dosing, and long-term safety profile. As the understanding of SGB’s role in sleep regulation evolves, it is hoped that clearer guidelines and evidence will emerge to support its use in clinical practice.

Written by: Joey Fio, Chief Programs Officer

References

[1] Lipov, E., Joshi, J. R., Sanders, S., & Slavin, K. V. (2008). A unifying theory of the role of the stellate ganglion block in treating PTSD, hot flashes, and sleep disturbances. Medical Hypotheses, 70(5), 955-959.

[2] Mulvaney, S. W., Lynch, J. H., Hickey, M. J., Rahman-Rawlins, T., Schroeder, M., Kane, S., & Lipov, E. (2014). Stellate ganglion block used to treat symptoms associated with combat-related post-traumatic stress disorder: a case series of 166 patients. Military Medicine, 179(10), 1133-1140.

[3] Hickey, A., Saunders, C., & Binns, J. (2020). Stellate Ganglion Block in the Management of Chronic Pain. Pain Management Nursing, 21(3), 233-238.

Commentary

The theory posits that administering Stellate Ganglion Block (SGB) treatment leads to a reduction in stress levels, which in turn decreases cortisol production in patients. This hormonal shift facilitates an environment conducive to improved sleep quality. Essentially, by mitigating the body’s stress response through the modulation of the sympathetic nervous system, SGB helps in lowering cortisol, a stress hormone known to interfere with sleep patterns. Consequently, this decrease in cortisol levels allows patients to experience better, more restorative sleep, addressing issues related to insomnia and sleep disturbances commonly associated with high stress and anxiety levels.

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